Lecturer

Cell biology

 

2004-2008, Bachelor, College of Life Science, Wuhan University, China

2008-2013, Ph.D., Institute of Biophysics, Chinese Academy of Sciences (CAS), China

2013-2015, Research assistant professor, Institute of Genetics and Developmental Biology, CAS, China

2015-present, Lecturer, Department of Cell Biology, College of Life Science, Beijing Normal University, China

 

Research Interests

Proteasomal degradation; Autophagy and Apoptosis; Transcriptional regulation; Tumorigenesis.

 

Selected Publications

♦ Research Articles

1. Jiang, T.X., ..., Goldberg*, A.L. and Qiu, X.B*. (2019). SIP/CacyBP promotes autophagy by regulating levels of BRUCE/Apollon, which stimulates LC3-I degradation. Proc. Natl. Acad. Sci. USA 116(27):13404-13413.

2. Jiang, T.X.*, Zhao, M., and Qiu, X.B*. (2018). Substrate receptors of proteasomes. Biological Reviews 93, 1765-1777.

3. Jiang, T.X,…, Yan XY*. (2012). CD146 is a coreceptor for VEGFR-2 in tumor angiogenesis. Blood, Sep 13;120(11):2330-9.

4. Zijian Li, Luming Zhou, Tian-xia Jiang, Xiaobo Qiu*. (2019). Proteasomal deubiquitinase UCH37 inhibits degradation of β-catenin and promotes cell proliferation and motility., Acta Biochim Biophys Sin , Volume 51, Issue 3, 277–284.

5. Yesheng Yin†, Qianqian Zhu†, Tian-xia Jiang, Libin Fan* & Xiaobo Qiu*. (2019). Targeting histones for degradation in cancer cells as a novel strategy in cancer treatment. Science China Life Sciences, Aug;62(8):1078-1086.

6. Ya-nan Liang,Yue Zhuang, Tian-xia Jjiang *, Xiao-bo Qiu *. (2017). Long Noncoding RNA YLB regulates expression of multiple genes in subtelomeric region.中国生化药物杂志，2017.01.001

7. Jie Zhuang, Tian-xia Jiang, Yan XY et al.. (2010). NADPH oxidase 4 mediates reactive oxygen species induction of CD146 dimerization in VEGF signal transduction. Free radical biology & medicine 49, 227-236.

 

♦ Reviews

1. Jiang, T.X.*, Zhao, M., and Qiu, X.B*. (2018). Substrate receptors of proteasomes. Biological Reviews 93, 1765-1777.

 

Contact Information

College of Life Sciences,

Beijing Normal University,

Beijing 100875,

P. R. China

Tel. : +86-10-58808117

E-mail: jiangtx@bnu.edu.cn